Alternative splicing - This lecture explains about the alternative splicing process to generate different varieties of mRNA from a single gene. Alternative splicing is a regulated approach for the duration of gene expression that results in a single gene coding for more than one proteins. In this approach, designated exons of a gene could also be included inside or excluded from the final, processed messenger RNA (mRNA) made from that gene.Accordingly the proteins translated from then again spliced mRNAs will include variations in their amino acid sequence and, most likely, of their biological services (see figure). Mainly, alternative splicing makes it possible for the human genome to direct the synthesis of many extra proteins than would be anticipated from its 20,000 protein-coding genes. Replacement splicing is mostly termed differential splicing.
Watch this video lecture to understand the mechanism of alternative splicing.
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Thank you for watching the alternative splicing mechanism in details.