New Coronavirus Mutation in England | Should we be concerned about this genetic variant?

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Anthony Kuster
Published at : 21 Dec 2020
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A new variant of the #coronavirus has been identified in southeast #England. The lineage of the virus has been named B.1.1.7. This lineage contains 17 defining mutations and at least three critical changes to the Spike protein. Most notably is the #N501Y mutation to the Spike Protein.

The new string has been cited as justification for Tier 4 restrictions in the UK, covering greater London and southeast England. Effectively one third of the UK is under #lockdown through Christmas.

But, where did these mutations come from? And are these mutations really causing increased infections in England? Should we be concerned about this genetic variant of the virus? These are the question that are answered in this video.


Sources include:

Preliminary genomic characterisation of an emergent SARS-CoV-2 lineage in the UK defined by a novel set of spike mutations | https://virological.org/t/preliminary-genomic-characterisation-of-an-emergent-sars-cov-2-lineage-in-the-uk-defined-by-a-novel-set-of-spike-mutations/563

Evolutionary virologist Dr. Emma Hodcroft: https://twitter.com/firefoxx66/status/1338533710178775047

The Science Behind London’s Christmas Lockdown | https://www.forbes.com/sites/johndrake/2020/12/19/the-science-behind-londons-christmas-lockdown/?sh=57349e62401c

Genomic epidemiology of hCoV-19 | https://www.gisaid.org/epiflu-applications/phylodynamics/

No evidence for increased transmissibility from recurrent mutations in SARS-CoV-2 | https://www.nature.com/articles/s41467-020-19818-2

Covid-19: New coronavirus variant is identified in UK | https://www.bmj.com/content/371/bmj.m4857

Boris Johnson Tightens U.K. Lockdown, Citing Fast-Spreading Version of Virus | https://www.nytimes.com/2020/12/19/world/europe/coronavirus-uk-new-variant.html
coronavirus mutation ukcoronavirus mutation englandn501y

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